NUR LAILATUL ISTIQOMAH Pengarang Prof. Dr.apt.Elin Yulinah Sukandar Dosen Pembimbing 1 apt.Atun Qowiyyah, M.Si Dosen Pembimbing 2

The liver is an important organ in the body which can experience hepatotoxicity, so we need a material that can protect and prevent liver damage known as a hepatoprotector. Several medicinal plants are reported to have hepatoprotector effects, including plants from the Fabaceae family. The purpose of this review article was to find scientific information about medicinal plants from the fabaceae family that have activity as a hepatoprotector. The method used was through online search of related journals from accredited websites such as Google Scholar, Science Direct, Elsevier, NCBI, Reaserch gate and Proquest. The results showed that 15 plants from the subfamily Caesalpinioideae, 8 from the subfamily Papilionoideae and 1 from the Mimosaceae subfamily had hepatoprotector activity through in vivo testing on experimental animals with various test parameters. The parts of the plant studied are leaves, roots, flowers, seeds, wood, fruit and herbs. The extraction solvents used include ethanol, methanol, aquadest, petroleum ether, chloroform, and ethyl acetate. The hepatotoxic inductors used include paracetamol and carbon tetrachloride (CCl4). It can be concluded that 24 species from the Fabaceae family have hepatoprotector activity, 2 species from the genus Cassia have been tested for their toxicity, and the active hepatoprotector compound from Cassia tora L. has been isolated, namely ononitol monohydrate.